Direct synthesis of pyridines and quinolines by coupling of γ-amino-alcohols with secondary alcohols liberating H2 catalyzed by ruthenium pincer complexes.

نویسندگان

  • Dipankar Srimani
  • Yehoshoa Ben-David
  • David Milstein
چکیده

A novel, one-step synthesis of substituted pyridine- and quinoline-derivatives was achieved by acceptorless dehydrogenative coupling of γ-aminoalcohols with secondary alcohols. The reaction involves consecutive C-N and C-C bond formation, catalyzed by a bipyridyl-based ruthenium pincer complex with a base.

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عنوان ژورنال:
  • Chemical communications

دوره 49 59  شماره 

صفحات  -

تاریخ انتشار 2013